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Karen is Plankton's computer wife, and she finds him annoying, stupid, twerp, moron, bad replacement, and nagger. She is either connected on the wall inside of the Chum Bucket, or on a cart with wheels moving around all the time by herself. Her cart comes with built-in arms. She stores memory on her hard drive, and she was only installed on their third date. She ran away from him in one episode, and returned in the next movie. She left him for 8 episodes, and was used as a sign holder that said Jackass, give me money now, and still didn't work out for her.

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